Kills your Cash on Cash Return on Investment (CoC ROI), @Patrick Kavanagh Foster. In less risky, well appreciating markets, this may still be a good move, but you have to know what compromises you're making when you go in.
@Patrick Kavanagh Foster It's niether good nor bad. It all depends on the situation and your goals. One can argue that it isn't the most efficient use of your funds but there may be circumstances where it does make sense to force additional cashflow by using a larger down payment.