My fairly new tenant CAN'T PAY rent

This has been an ongoing issue since the beginning and I'm learning the hard way to screen tenants properly. A family began to rent our newly built house in June and after about a month, the wife had been diagnosed with a serious medical condition. Getting rents on time was rough but we managed to get all the rents so far. 

I received a phone call today from them and let me know that the husband got laid off and there are more medical bills to pay.. and a lot of sad stories. And that they aren't able to pay the whole amount on the 1st. 

I did receive a total of 2 months worth of rent upfront (1 month security deposit + 1 month rent). I'm trying to understand their sad situation but at the same time, there are bills to pay. 

I'm reading our lease agreement and there isn't a specific area regarding breaking the lease. I want them to use the last month rent that they paid in the beginning and leave and find a new place at the end of November. 

Any sound advice from seasoned landlords would be greatly appreciated.