Payment Options 50% or 100% at time of booking

I'm going through my Lodgify payment settings and was wondering if anyone had thoughts on whether or not having a partial payment at time of booking or charging for the full booking made any difference? 

My VRBO does 2 payments and I've never had any issues with it, but did see some folks talking about VRBO sending check-in info when the 2nd payment hadn't been paid. Can obviously mitigate access to the property by disabling the code if using a smart lock, but other than that, are there any advantages/disadvantages that you've seen?