I've seen one of my clients (a start-up hub) turn the vault into a conference room while I've seen another use the vault for storage.

When I have clients asking which option I would suggest, it usually comes down to whether the property is near a business hub (like RTP, in my case), or within five to seven minutes of a hospital or university.

Big employers include The Limited (Victoria's Secret, Bath & Body), Nationwide Insurance HQ, Worthington Industries, Honda of America, State Farm, MANY others including a fast growing TEHNOLOGY hub that is attracting millennials, and Capital Unviersity, Ohio State, DeVry, Franklin University, Otterbein College, Columbus College of Art Design, PLUS medical OSU Hospital and James Cancer Center, Riverside Methodist Hospital, St.Anne's Hospital, Grant Hospital, etc. 

I do know that Cleveland is enjoying an economic revival based on healthcare (Cleveland clinic regional hub), but long-term, I don't know what that will translate into population-wise. 

They picked the location for a reason however, it is at the hub of two toll Roads (414 and 429) and is surrounded by lots of land for medical offices and naturally residential is growing in the area too. 

We also have a major University in the town and it is the central hub for the surrounding areas.

(Here is a good article detailing startup and ongoing costs - https://www.realestateexpress.com/career-hub/become-a-real-estate-agent/7-costs-to-consider-when-starting-a-real-estate-career/)So I guess I'll close with this...your idea to get a license will work if you plan to make enough money to cover the costs.

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Seattle is a tech industry hub.

All of that being said, from an investor's standpoint, Philadelphia is one of the lowest priced major cities in the Northeast, it has easy access to other major cities and industry hubs (NYC and DC), amenities are amazing (access to hospitals, beaches, parks, rivers, museums, restaurants, etc.) and the market is booming (Expats from NYC and other high priced cities).