Yeah - the 405 can be rough. I never drive on it during the busiest hours.
1. I don't have any of my own personal properties near colleges and so I aim to rent to anyone - no college targeting. Plus I can't envision any college students wanting to rent from me as the properties aren't near them. But if a student applied, had a strong application (co-signing parents or the student worked) and I liked them I'd likely rent to them. Also, randomly, with my newest multi-unit my insurance agent asked if I'd be renting to college students. I said no but he did point out the plan I had (some smaller insurance company located in Pennsylvania I had never heard of) would mean higher premiums if I did.
Some insurers evidently don't like it. My family owns some properties and some were aimed at renting to college students and there were never any problems minus the carpet getting trashed because of heavy shoe traffic) but college students typically rented for years at a time and we had better experiences renting to them as opposed to non-college students.
2. Everything I've bought has been 'almost move in ready'. There's typically minor work I didn't ask for the seller to fix (cosmetic, small fixes, minor electrical like restoring non-working power to the garage for a property - no clue how the inspector missed that one, etc.). I don't like to buy homes that need a lot of work. I think that idea works better in hotter markets or markets where the work justifies the return (like O.C. or L.A., for example).
Though I know of people who have done it in Erie (one guy bought a bunch of apartment buildings off West 12th near I-79 years ago - they were supposedly trashed on the inside - nice brick buildings that were more like townhouses) and spent a lot of money fixing them up but from what my dad's told me the guy has done well in doing so. So there are exceptions to every rule (and as we know multis tend to cashflow better than a SFR).
But you're correct - Erie has a lot of over-priced, crap homes on the MLS that have underwhelming returns. The good news is this is the best time of year to buy. There's no reason why you can't achieve the 2% rule in Erie with a property that's in a halfway-decent neighborhood. You just need to do what Brandon Turner (the guy who does the Bigger Pocket webinars) does and keep searching for deals, doing what others don't do (such as sending out mailers, calling 'absentee landlords', etc.).
I don't know who is building the properties near Behrend but they're building large apartment buildings. One's across the street. Research could be done to learn who's doing it. The owners of Lecom are buying a lot of properties (the Ferrettis) because LECOM keeps growing. As you can see properties around LECOM sell well and are often purchased quicker.
I also recommend you join The Apartment Association of NW PA as they're a great source for contracts, local landlord laws, credit reports, etc. And they would have better knowledge than me pertaining to the heavy-hitters who have apartment buildings including ones catering to college students.