Only scenario I can think of is a 2-4 units (duplex/triplex/4plex) where you live in one of the units and the investor gets the cash-flow from the other units.
We have a FHA 203k loan on our multi-family home. Yes, it must be your primary residence and you must live there for a required period of time. We are now at the point of refinancing to a conventional loan to get rid of the manditory mortgage insurance and purchase another multi-family property with a FHA 203k loan. I believe you can do this type of loan up to 7 times. There's alot of paperwork, but it's worth doing.