Lots of gentrification opportunities in some of the older part south of Milwaukee where the old manufacturing used to be. 

Cleveland, Toledo, Dayton, Cincinnati and Columbus all have affordable real estate markets that are largely driven by local economic conditions and the health of the city's manufacturing industry.

I also have worked with realtors in Columbus and with the Intel Investment in New Albany Ohio with what will become the largest chip manufacturer in the world there is a lot of price appreciation that will be coming to that area.

Quote from @Harrison Chow: Toledo, on the other hand, features a stable and diverse economy, driven by industries such as healthcare, manufacturing, and education.

Intel is a great example, who is building the largest chip manufacturing plant in the US right here, and it will be a $20 billion dollar investment that brings a few new thousand jobs.https://www.dispatch.com/story/business/2022/01/21/intel-ohio-building-computer-chip-factories-licking-county-jersey-township/9173472002/ Another example of economic growth is the upcoming Ohio State University Wexner Medical Center Inpatient Hospital which is a 1.9million square foot hospital that will bring over 800 new beds and a thousand new jobs. https://abc6onyourside.com/news/local/new-osu-hospital-expected-to-transform-health-careHere are a few more recent investments https://www.10tv.com/article/money/business/hydrogen-power-company-hyperion-bringing-700-jobs-to-columbus/530-25907aab-5517-4661-a9f3-d2ed2d5be6b0 https://news.wosu.org/news/2022-02-08/rumpke-to-build-50-million-recycling-facility-in-columbus Check out The Complete Guide to the Columbus, Ohio Real Estate Market which goes through the Columbus, Ohio market in depth and will give you a better scope of where the highest levels of growth are taking place and where to look to invest.

The number of workers in most industries - automotive, manufacturing, etc - has either stagnated or declined, while the level of output has increased fairly dramatically.

When the city was first founded there was a big rush of glass manufacturers to the area.

They are manufactured in a huge factory to spec. 

I have been building remote teams for a long time in manufacturing projects and it is really a matter of how well you can motivate the people on the team and at the same time trust them, even though you are not around and they know that.

I have heard from steel manufacturers and distributors, that they are terrified of the tariffs expiring, as they will flood the market.